Our research is focused on the epigenetic events driven by PARylation for the control of gene expression

Research fields

1)      role of PARylation in the control of DNA methylation and DNA hydroxymethylation

2)      analysis of the cross-talk between CTCF/BORIS and PARP-1 for the control of genes involved in pathological events

3)       involvement of PARylation in the epigenetic deregulation occurring in Multiple Sclerosis

4)      PARylation and ageing