1) Cell and DNA damage: the poly-ADP-ribosylation System as epigenetic  regulatory mechanism and its correlation with cancer and apoptosis.

2) Analysis of oxidative stress and anti-oxidant defense in plants and animals: the poly-ADP-ribosylation system in prokaryotes and eukaryotes, and cell membrane lipid analysis as tools to study the physio-pathological state of the cell.

3) Identification of new biomarkers of environmental soil and water pollution.